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Spectrum: Autism Research News

News Archive

October 2009

Fragile X mice marked by immature synapses

by  /  21 October 2009

Young mice that mimic fragile X syndrome have immature and unstable dendritic spines, the neuronal branches that receive signals from other cells, according to unpublished research presented Tuesday at the Society for Neuroscience meeting in Chicago.

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Postmortem study hints at two types of autism

by  /  21 October 2009

The brains of people with autism show high levels of inflammation compared with controls, suggests a study of postmortem brain tissue from 11 individuals with autism, presented at a poster session Monday at the Society for Neuroscience meeting in Chicago.

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MeCP2 loss ups inhibitory signaling

by  /  21 October 2009

Selectively disrupting an autism-related gene in cultured human neurons causes a dramatic imbalance of excitation and inhibition in cell signaling, according to unpublished results presented today at the Society for Neuroscience meeting in Chicago.

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Neuroligin mutation triggers oxidative stress

by  /  20 October 2009

Deleting a neuronal protein associated with autism causes oxidative stress — characterized by an excess of free radicals — which has been linked to diseases such as diabetes and Alzheimer’s, according to new research in worms. The results were presented yesterday at a poster session at the Society for Neuroscience meeting in Chicago.

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Lack of corpus callosum linked to autistic features

by  /  20 October 2009

People born without the large bundle of nerve fibers that bridges the brain’s hemispheres have trouble identifying fearful faces, and don’t look preferentially at others’ eyes to perform this task, according to research presented Sunday at the Society for Neuroscience meeting in Chicago.

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Video: NIH director bemoans ‘lack of trust’ in autism field

by  /  20 October 2009

On Saturday, a top government official resigned from the Interagency Autism Coordination Committee, the body of scientists and advocates that’s responsible for guiding all autism research funded by the U.S. National Institutes of Health. Institute director Francis Collins responds.

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Immune activation triggers autism features in mice

by  /  20 October 2009

Mice carrying an autism-associated mutation show impaired social interactions and dramatic changes in brain size when their immune systems are activated, according to research presented yesterday at a poster session at the Society for Neuroscience meeting in Chicago.

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Video: The challenge of autism’s enormous variability

by  /  20 October 2009

After a Monday afternoon poster session at the Society for Neuroscience meeting in Chicago, Noboru Hiroi talked about the challenges of following up human genetic findings in the mouse.

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Language gene linked to interneuron growth

by  /  20 October 2009

A gene tied to autism and language impairment is crucial for the early development and migration of inhibitory interneurons, according to research presented Monday at the Society for Neuroscience meeting in Chicago.

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Therapies reverse autism in mouse model

by  /  19 October 2009

New pharmacological and behavioral interventions can reverse characteristics of autism in a mouse model of the disorder, according to unpublished results presented in poster sessions today at the Society for Neuroscience meeting.

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