Skip to main content

Spectrum: Autism Research News

Tag: Angelman syndrome

November 2018
View of San Diego in twilight.

Takeaways from SfN 2018

by  /  12 November 2018

After the presentation of more than 14,000 abstracts over five days, the Society for Neuroscience annual meeting in San Diego ended last week.


Stem cells could deliver gene therapy for Angelman syndrome

by  /  7 November 2018

Modified stem cells show promise for delivering gene-based therapies to individuals with Angelman syndrome.

Mice in a lab test on a rotarod.

Careful mouse tests could forecast fate of Angelman drugs

by  /  2 November 2018

A new protocol enables researchers to rigorously test drugs for Angelman syndrome in mice.

October 2018
An illustration shows a mosaic-like view of viruses delivering genes to the brain.

Angelman syndrome: Bellwether for genetic therapy in autism

by ,  /  16 October 2018

It is not a matter of whether there will be clinical trials of genetic therapy for Angelman syndrome, but when.

September 2018
Mouse brain slices glow green and blue in microscope view.

Cancer drug finds new use as treatment for Angelman syndrome

by  /  26 September 2018

Compounds that mimic a cancer drug restore expression of the key gene mutated in Angelman syndrome, a condition related to autism.

August 2018
Group of people in medical waiting room.

New diagnostic code for Angelman syndrome may spark crucial research

by  /  15 August 2018

The international manual of conditions now includes a diagnostic code for Angelman syndrome — which may enable scientists to systematically collect information about the syndrome.

November 2017
closed eye and wide open eye against sky

Autism may disrupt the body’s circadian clock

by  /  13 November 2017

Sleep problems in autism may stem from the same biological changes that underlie the core features of the condition.


Electronic glow may disrupt sleep for people on the spectrum

by  /  13 November 2017

Exposure to certain types of light at night may exacerbate sleep issues among people with autism.

Mice that lack UBE3A only in their inhibitory neurons are particularly susceptible to seizures.

Gene therapy technique prevents seizures in Angelman mice

by  /  12 November 2017

Introducing the gene UBE3A into neurons that dampen brain activity prevents seizures in a mouse model of Angelman syndrome.

October 2017
Toddler girl sleeping with hair floating against black background.

How treating sleep may ease all forms of autism

by  /  31 October 2017

Behavioral interventions and medications can help children with autism-related syndromes sleep better, but the treatments must be tailored to the cause of each child’s sleep disturbance.