Mice that model Angelman syndrome, an autism-related disorder, are more motivated to earn rewards than controls are, according to unpublished results presented Wednesday at the 2012 Society for Neuroscience annual meeting in New Orleans.
Spectrum: Autism Research News
Tag: Angelman syndrome
After nine long years, the Society for Neuroscience annual meeting is returning to New Orleans. And SFARI.org’s reporters are ready to deliver the best advances in autism research that emerge.
Mice that model Angelman syndrome or have a duplication of the 15q11-13 chromosomal region have aberrant brain levels of the chemical messenger serotonin, according to a study published 16 August in PLoS One.
Deleting CYFIP1, a gene within a region linked to Angelman syndrome and autism, in mice leads to symptoms reminiscent of fragile X syndrome, according to a study published 10 August in PLoS One.
Researchers plan to develop pig models of Prader-Willi syndrome, an inherited disorder caused by the deletion of an autism-linked region of chromosome 15.
Researchers are beginning to tease apart how dosage of genes within the 15q11-13 chromosomal region contributes to autism symptoms.
Concerned by researchers’ lack of access to a valuable mouse model of autism, a nonprofit advocacy group is dedicating a chunk of its limited resources to the creation of a freely available version.
Mice lacking a functional copy of UBE3A, the gene missing or mutated in people with the rare developmental disorder Angelman syndrome, show less inhibitory activity than controls do, according to research published 7 June in Neuron.
A high intelligence quotient, a good understanding of social skills, and aggressiveness may all contribute to anxiety in children with autism, according to a study published 14 March in The Journal of Clinical Child and Adolescent Psychiatry.