A new method for turning brains transparent and scanning them will make it easier to map neuronal circuits, according to a paper published 24 April in Cell.
Spectrum: Autism Research News
Mutations in two proteins that help guide neurons as they grow in the developing brain may be risk factors for autism, according to a study published 14 January in Human Molecular Genetics.
Electrical signals generated by dendrites, the branches of neurons that receive information from neighboring cells, may help neurons tune their responses to stimuli, according to a study published 7 November in Nature.
Studies at the level of neural circuits are needed to better understand the importance of both increased and decreased connectivity between different regions in the autism brain, say John Rubenstein and Vikaas Sohal.
Depleting excess levels of a molecule involved in neuronal signaling prevents the cognitive and motor symptoms of Angelman syndrome in a mouse model of the disorder, according to a report published 15 August in Cell Reports.
The autism-linked protein MET is expressed at the junctions between neurons during early brain development in mice, suggesting that it helps establish the connections, according to a study published 21 June in The Journal of Comparative Neurology.