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Spectrum: Autism Research News

Tag: axons

August 2012

Molecular mechanisms: Study links RAS pathway to autism

by  /  8 August 2012

An autism-linked mutation in the signaling protein EPAC2 alters the shape of neuronal branches, according to a study published in the June issue of PLoS Biology.

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Cognition and behavior: Connectivity deficits link autism, TSC

by  /  7 August 2012

Abnormalities in the connections between language-related brain regions are similar in people with autism and those with tuberous sclerosis, a genetic disorder characterized by benign tumors throughout the brain and body, according to a paper published 1 June in Cerebral Cortex.

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July 2012

Molecular mechanisms: Autism gene regulates neuron shape

by  /  31 July 2012

TAOK2, a gene in the autism-associated 16p11.2 chromosomal region, is part of a signaling pathway that builds neuronal connections during development, according to a study published 10 June in Nature Neuroscience.

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Tuberous sclerosis gene loss triggers autism-like features

by  /  26 July 2012

Losing one or both copies of TSC1, one of the two genes responsible for tuberous sclerosis complex, in specific cells of the cerebellum can trigger several autism-like behaviors in mice, according to research published 1 July in Nature.

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Insights for autism from tuberous sclerosis complex

by  /  24 July 2012

Studying tuberous sclerosis provides researchers with a unique opportunity to find a common pathway among the various genetic causes of autism, says neurologist Mustafa Sahin.

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May 2012

Cognition and behavior: Language links differ in autism brains

by  /  15 May 2012

The bundles of nerve fibers that connect two regions important for language are abnormal in the brains of children with autism, according to a study published 5 April in the American Journal of Neuroradiology.

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March 2012

Brain imaging reveals simple organization for neural wires

by  /  29 March 2012

Rather than a tangled bowl of spaghetti, the neural wiring in the brain is arranged in an orderly fashion, like a woven piece of cloth, according to research published today in the journal Science.

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February 2012

Brain game

by  /  14 February 2012

A new website invites the public to help map the ‘connectome,’ the pattern of connections among all the neurons in our brain.

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Clinical research: Two compounds treat Rett syndrome in mice

by  /  1 February 2012

Two compounds that enhance the activity of BDNF, a protein needed for the growth of neurons, improve motor skills in mouse models of Rett syndrome and increase the mice’s lifespan.

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January 2012

Molecular mechanisms: Autism gene tied to neuronal junctions

by  /  24 January 2012

Neurobeachin, or NBEA, an autism–associated gene, may regulate the transport of signaling molecules to neuronal branches, according to a study published 22 November in Nature Communications.

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