A new wiring diagram of the mouse brain could help autism researchers better study how brain connections vary in mice with different genetic backgrounds.
Spectrum: Autism Research News
Tag: BTBR mice
Many researchers question the value of three early mouse models of autism, but the models have their staunch supporters.
Watch the complete replay of William Catterall explaining how low doses of an anxiety drug alleviate autism-like symptoms in mice.
Two new studies give a boost to arbaclofen, which failed to meet expectations in clinical trials for autism and fragile X syndrome.
As the number of autism rodent models climbs, it is a good time for the field to step back and consider the best practices for assessing autism-like symptoms in rodents, says Jacqueline Crawley.
Mice modeling autism have trouble integrating different kinds of sensory information such as sight, sound and touch. A study published 31 July in Neuron reports that an imbalance between signals that calm neurons and those that excite them leads to these sensory problems.
A new tracking system automatically logs and scores mouse behavior as well as a human observer does, according to a paper published 31 December 2013 in Journal of Neuroscience Methods.
Rapamycin, a drug given to suppress immune rejection after transplants, improves social behavior in mice with features of autism, reports a study published in the January issue of Brain Research Bulletin.