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Spectrum: Autism Research News

Tag: BTBR mice

January 2021
Mouse brain scan video still in black and white.

New mouse brain atlas traces connections in fine detail

by  /  13 January 2021

A new wiring diagram of the mouse brain could help autism researchers better study how brain connections vary in mice with different genetic backgrounds.

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March 2018
illustration of mouse on sale in a city

‘Outmoded’ mouse models of autism may still yield new advances

by  /  21 March 2018

Many researchers question the value of three early mouse models of autism, but the models have their staunch supporters.

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June 2015

William Catterall examines anxiety drugs for autism

24 June 2015

Watch the complete replay of William Catterall explaining how low doses of an anxiety drug alleviate autism-like symptoms in mice.

5 Comments
April 2015

Mouse studies support second chance for fragile X drug

by  /  28 April 2015

Two new studies give a boost to arbaclofen, which failed to meet expectations in clinical trials for autism and fragile X syndrome.

6 Comments
October 2014

How early should autism treatment begin?

by  /  15 October 2014

The preliminary success of a therapy designed to help infants with symptoms of autism raises broader questions about the potential promise and many challenges of early intervention.

8 Comments
September 2014
Mouse lab test: the three chambered assay

Optimizing behavioral assays for mouse models of autism

by  /  23 September 2014

As the number of autism rodent models climbs, it is a good time for the field to step back and consider the best practices for assessing autism-like symptoms in rodents, says Jacqueline Crawley.

3 Comments
August 2014

Signaling imbalance skews sensory responses in autism mice

by  /  11 August 2014

Mice modeling autism have trouble integrating different kinds of sensory information such as sight, sound and touch. A study published 31 July in Neuron reports that an imbalance between signals that calm neurons and those that excite them leads to these sensory problems.

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April 2014

Low-dose sedative eases autism symptoms in mice

by  /  3 April 2014

The equivalent of one-tenth of a single pill of the anxiety drug clonazepam alleviates many autism-like behaviors in a mouse model of the disorder, according to a study published 19 March in Neuron.

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February 2014

Automated tool records behavior of autism mouse models

by  /  5 February 2014

A new tracking system automatically logs and scores mouse behavior as well as a human observer does, according to a paper published 31 December 2013 in Journal of Neuroscience Methods.

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January 2014

Cognition and behavior: Drug ups sociability in autism mice

by  /  31 January 2014

Rapamycin, a drug given to suppress immune rejection after transplants, improves social behavior in mice with features of autism, reports a study published in the January issue of Brain Research Bulletin.

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