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Spectrum: Autism Research News

Tag: cancer

October 2013

Length matters: Disease implications for long genes

by  /  22 October 2013

A gene’s length may influence its expression, and this has implications for autism, which tends to be linked to particularly long genes, says Mark Zylka. 

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Cancer pathway connects autism to set of rare disorders

by  /  21 October 2013

About one in four people diagnosed with a group of rare disorders have autism, according to a study published 7 October in the Journal of Medical Genetics. The disorders all affect a single cancer-related pathway, driven by a protein called RAS.

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September 2013

In autism-related disorders, RNA turns out to be key

by  /  26 September 2013

An enzyme that may keep RNA tangle-free as it’s translated into protein is missing in some people with schizophrenia and learning difficulties. The enzyme also cooperates with the protein missing in fragile X syndrome to bind RNA, suggesting a role in protein synthesis. That’s the upshot from two studies published in the September Nature Neuroscience.

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Aging fathers, selfish testes and neurocognitive disorders

by  /  24 September 2013

Certain mutations may hijack the normal mechanisms of sperm production, leading to an enrichment of mutant sperm in older fathers, and to the paternal-age effect in autism.

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Molecular mechanisms: Study shows Angelman drug’s actions

by  /  24 September 2013

Researchers have uncovered the mechanism by which a candidate drug for Angelman syndrome activates UBE3A, the gene that is silenced in the syndrome, according to a study published 20 August in the Proceedings of the National Academy of Sciences.

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July 2012

Insights for autism from tuberous sclerosis complex

by  /  24 July 2012

Studying tuberous sclerosis provides researchers with a unique opportunity to find a common pathway among the various genetic causes of autism, says neurologist Mustafa Sahin.

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April 2012

Molecular mechanisms: Autism gene modulates connectivity

by  /  10 April 2012

Neurons lacking PTEN, an autism-associated gene also involved in cancer, are hyperconnected to both near and distant brain cells, according to a study published 1 February in The Journal of Neuroscience.

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May 2011

Trendsetters

by  /  6 May 2011

Of 72 newly elected members of the National Academy of Sciences, 7 work either directly on autism or in related areas, illustrating the growing intellectual breadth and depth of the field.

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March 2011

Empathy gap

by  /  18 March 2011

A new study shows that just a little bit of testosterone administered under the tongue can lower a woman’s skills at interpreting another person’s emotional state — especially if she has been exposed to high levels of testosterone in utero.

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February 2011

Window into brain reveals real-time growth of neurons

by  /  15 February 2011

A new technique allows researchers to watch the long-term effects of disease on the brain, according to a study published in the February Nature Medicine. The approach could help scientists study changes in the brain that result from neurological disorders such as autism.

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