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Spectrum: Autism Research News

Tag: cerebellum

September 2021

Placental hormone loss spurs autism-like traits in mice

by  /  2 September 2021

Mice exposed to unusually low levels of the placental hormone allopregnanolone in the womb show atypical brain development and autism-like behaviors.

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August 2021

Molecular overlap links tuberous sclerosis, fragile X

by  /  16 August 2021

Brain cells from the cerebellums of mice that model tuberous sclerosis show dampened levels of proteins controlled by FMRP, the protein missing in fragile X syndrome.

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April 2021

Loss of CHD8 from cerebellum disrupts movements, not social behaviors

by  /  26 April 2021

Deleting the autism-linked gene CHD8 from specific cells in the cerebellum, a brain region important for movement, leads to motor deficits but does not alter social behaviors in mice.

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February 2021
Oligodendrocyte gene grouping showing network of blue lines connecting the gene names on reddish bubbles.

Differing gene functions across species may pose problems for autism models

by  /  22 February 2021

Misaligned gene expression maps suggest that some autism-linked genes play distinct roles in mouse and human brains.

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January 2021
Baby getting an MRI scan

Imaging study casts doubt on cerebellum’s role in autism during infancy

by  /  13 January 2021

Connections between the cerebellum and brain networks do not seem to contribute substantially to the emergence of autism traits.

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Neurons in cerebella of mice with fewer branches and spines.

Cerebellum alterations crop up in mice missing autism gene

by  /  12 January 2021

Deleting the autism-linked gene CNTNAP2 from mice leads to distinct cellular and electrical changes in the cerebellum, according to two unpublished studies presented virtually today at the 2021 Society for Neuroscience Global Connectome.

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Senior man lying down in scanning machine.

Studies hint at effects of aging on autistic brains

by  /  12 January 2021

People with autism or autism traits may be especially vulnerable to brain aging and cognitive decline, two studies suggest.

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lab mice

Mice with autism-related mutations show brain signaling imbalance

by  /  4 January 2021

Mutations in POGZ, a gene strongly linked to autism, lead to a signaling imbalance in multiple brain regions in mice, according to two new studies.

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December 2020
researcher facing off with the coronavirus.

Rewind: Spectrum’s best from 2020

23 December 2020

Our staff picks the stories, podcasts and special reports that stood out from the rest this past year.

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Micrograph of nerve cells being targeted by CRISPR enzyme to activate the silenced gene in Angelman syndrome

Hot topics in autism research, 2020

23 December 2020

The Spectrum team highlights five topics that distinguished autism research in 2020: diversity in data, gene therapies, subtyping, social circuitry and the ‘autism gene’ debate.

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