The largest set of exome sequencing studies of children with autism and their families to date has identified a handful of genes that may increase risk of the disorder, according to research published in Nature.
Spectrum: Autism Research News
Tag: common variants
Researchers have mapped networks of genes expressed at the same time and place in the brain and shown that rare and common autism-linked mutations are likely to function in the same pathways. The results were published 8 March in PLoS Genetics.
The genetic risk factors for autism may also increase a person’s risk of developing ankylosing spondylitis, a form of arthritis of the spine, and decrease the risk of multiple sclerosis, according to a study published 13 December in Translational Psychiatry.
TBL1X, a gene located on the X chromosome, is associated with autism in males but not in females, according to a study published 3 November in Molecular Autism.
Three variants of DISC1, a gene implicated in schizophrenia and autism, may disrupt the formation of new neurons in the brain, according to a study published 17 November in Neuron.
Individuals with autism-linked variants of a language gene use regions in the brain’s right hemisphere, rather than the left, to process language, according to a study published 10 October in The American Journal of Medical Genetics Part B.