Variants that control gene expression are often involved in whether a mutation ends up being harmful, and how harmful it is.
Spectrum: Autism Research News
Tag: common variants
Software to identify genetic variants, along with a new synthetic human genome, could help scientists discover mutations associated with conditions such as autism.
Watch the complete replay of this journal club, which featured a paper exploring rare genetic variation in psychiatric conditions, including autism.
We must diversify databases of reference DNA to improve our ability to interpret the consequences of genetic variation.
Some individuals who have autism mutations show no signs of the condition; understanding why may lead to treatments.
Existing genome scans do not detect many of the DNA variants that underlie behavioral problems.
A widely used treatment for anxiety can eliminate some of the cognitive and social problems seen in mice missing a copy of ARID1B, a gene associated with autism.
Male mice with a genetic variant tied to autism may have learning difficulties that females with the variant do not.
Watch the complete replay of this journal club, which featured two papers that explore therapies for Rett syndrome.