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Spectrum: Autism Research News

Tag: connectivity

October 2021
Two mice in cage with one peeping out.

Brain stimulation improves memory in autism mouse models

by  /  15 October 2021

Jolting a bundle of nerve fibers deep in the brain restores learning and memory in mice with mutations of the autism-linked gene CDKL5.

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September 2021
Colorful image of a composite of multiple brain scans showing communication patterns in different regions.

Autism mouse models cluster by brain activity pattern

by  /  10 September 2021

Four subtypes lend new support to the idea that there isn’t a single ‘hallmark’ type of brain connectivity in people with autism.

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June 2021
Mouse neuron recordings showing different levels of activity before and after an encounter with an unfamiliar mouse.

Neural network captures noisy neurons in autism mouse model

by  /  18 June 2021

Mice missing the autism-linked gene SHANK3 use more neurons to engage in social behavior than control mice do, reflecting a more disorganized, less efficient brain signaling network.

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April 2021
Colorful RNA in mouse brain slice

Tissue-swelling method divulges RNA locations, sequences in cells

by  /  28 April 2021

A technique that expands tissue before spotting and sequencing RNA — the molecular messenger for DNA — enables researchers to see where particular genes are expressed in cells.

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February 2021
Mouse brains show different brain regions lighting up

Ultrasound probe reveals brain circuit activity in living mice

by  /  18 February 2021

A new high-resolution imaging device tracks brain activity in awake mice, enabling researchers to map neural circuits across the entire brain.

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January 2021
Mouse brain scan video still in black and white.

New mouse brain atlas traces connections in fine detail

by  /  13 January 2021

A new wiring diagram of the mouse brain could help autism researchers better study how brain connections vary in mice with different genetic backgrounds.

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Baby getting an MRI scan

Imaging study casts doubt on cerebellum’s role in autism during infancy

by  /  13 January 2021

Connections between the cerebellum and brain networks do not seem to contribute substantially to the emergence of autism traits.

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Senior man lying down in scanning machine.

Studies hint at effects of aging on autistic brains

by  /  12 January 2021

People with autism or autism traits may be especially vulnerable to brain aging and cognitive decline, two studies suggest.

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dopamine neurons in mice show up green in an area of the brain associated with social reward.

Dopamine neurons may dampen social behavior in mouse model of autism

by  /  12 January 2021

Mice missing a copy of the autism-linked gene PTEN show a reduced preference for social interaction, possibly due to atypically large, overconnected dopamine neurons. Easing the overconnection may alleviate this trait.

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November 2020
Brain diagrams showing connectivity within different regions.

Gene mutations point to overlaps in brain connectivity for autism, schizophrenia

by  /  30 November 2020

People who have large mutations associated with autism and schizophrenia share atypical patterns of brain connectivity, according to a new study, especially between areas that process sensory information.

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