Music therapy proves ineffective for autism, brain structures differ with 16p11.2 duplications and deletions, and mice missing NLGN3 may influence the sociability of their littermates.
Spectrum: Autism Research News
Tag: copy number variation
People who carry risk factors for autism but do not have the condition tend to have slightly fewer children than average, and have them later in life.
We finally have access to whole-genome sequences from people with autism. But before we can properly interpret these data, we need to know what we’re looking for.
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Children missing a stretch of DNA on chromosome 16 show worsening motor and social skills in the first eight years of life; those with an extra copy of the region do not show this decline.
Mutations in a gene called TRIP12 — which is involved in tagging proteins for destruction — can lead to intellectual disability, language delay and autism.
In children with a deletion on chromosome 22, having autism does not boost the risk of developing schizophrenia later in life.
An analysis of whole genomes from more than 5,000 people has unearthed 18 new candidate genes for autism.