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Spectrum: Autism Research News

Tag: cortex

January 2021
In cortical-striatal assembloids, striatal neurons (magenta) derived from individuals with Phelan-McDermid syndrome fire more frequently than neurons from controls.

Brain ‘assembloids’ capture circuit flaws in syndrome tied to autism

by  /  21 January 2021

Merging 3D clusters of neurons that mimic different brain regions models the atypical electrical activity seen in an autism-related condition.

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October 2020

Integrating molecular data may reveal subgroups of autism

by  /  30 October 2020

An analysis of four molecular datasets shows a distinct signature, including changes in gene expression and chemical DNA modifications, in some autism brains.

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four brain areas marked with flags: Cortex, amygdala, hippocampus, cerebellum

Brain structure changes in autism, explained

by  /  15 October 2020

Autistic people have distinct patterns of brain development, which sometimes result in differences in brain structure. Here’s what we know about those differences.

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neurons in green.

Brain organoids reveal neuronal flaws in syndrome tied to autism

by  /  12 October 2020

Neurons derived from people with 22q11.2 deletion syndrome show deficits in calcium signaling and electrical activity, pointing to possible therapeutic targets.

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Brain hemispheres color-coded.

Autism shares brain structure changes with other psychiatric conditions

by  /  1 October 2020

Atypical development of a particular type of neuron explains the structural similarities seen in the brains of people with autism, schizophrenia and other conditions, according to a new study.

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June 2020

Flexible implant records brain activity in rats for more than a year

by  /  3 June 2020

A new flexible electrode array can detect the activity of neurons in a rat’s brain at high resolution for more than a year.

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May 2020

Ultra-sensitive protein activates neurons in response to external light

by  /  27 May 2020

A new, minimally invasive technique allows researchers to activate neurons in the brains of mice and monkeys by using a light source located outside of the head.

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April 2020
four brain views, seen from the side.

Brain anatomy differences in autism may vary by age, sex

by  /  13 April 2020

Several regions in the outer layer of the brain are thicker in children and young adults with autism than in their typical peers.

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March 2020
Brain scans showing differences between those with TBR1 mutations and controls.

Mutations in top autism gene linked to changes in brain structure

by  /  4 March 2020

People with mutations in a gene called TBR1 have unusual features in several brain regions, along with autism traits and developmental delay.

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January 2020

How the autonomic nervous system may govern anxiety in autism

by ,  /  14 January 2020

The branch of the nervous system that regulates subconscious bodily processes such as breathing and digestion may play a key role in autism.

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