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Spectrum: Autism Research News

Tag: epigenetics

March 2014

Genetics: MicroRNA may suppress autism gene expression

by  /  25 March 2014

A small fragment of RNA may regulate the expression of RORA, a gene implicated in many autism-related pathways, according to a study published 6 February in Scientific Reports.

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Emerging importance of chromatin in autism risk

by ,  /  18 March 2014

Sequencing studies over the past few years have made a dramatic and unexpected discovery: Many of the mutations in individuals with autism are in genes that regulate chromatin, which helps package DNA in the cell nucleus, say Gerald Crabtree and Aryaman Shalizi.

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RNA binds to fragile X gene, shutting it down

by  /  13 March 2014

Misplaced pieces of RNA bind and disable the gene responsible for fragile X syndrome, leading to the disorder, according to a study published 28 February in Science.

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No longer junk: Role of long noncoding RNAs in autism risk

by ,  /  4 March 2014

Long pieces of RNA that do not code for protein have diverse and important roles in the cell and may contribute to autism risk, say Nikolaos Mellios and Mriganka Sur.

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February 2014

First 1,000 days of life could hold keys to autism

by  /  17 February 2014

Autism researchers have high hopes for a new project called the First 1,000 Days of Life, which aims to follow 5,000 women and their babies from pregnancy through two years after birth.

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Gut bacteria’s influence on brain development

by ,  /  4 February 2014

Researchers should consider the influence of gut bacteria on brain function, especially when studying neurodevelopmental disorders such as autism, say John Cryan and Roman Stilling.

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January 2014

Genetics: Methylation may alter levels of autism gene

by  /  28 January 2014

Postmortem brains from people with autism have abnormal patterns of chemical tags on SHANK3, one of the strongest candidate genes for autism, according to a study published 23 November in Human Molecular Genetics.

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December 2013

Analysis debunks link between autism, fertility treatments

by  /  10 December 2013

Studies with the best quality ratings and the largest sample sizes showed no increased risk of autism for children born from assisted reproductive technologies, reports a review published in the December issue of Human Reproduction.

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November 2013

Neurons made from teeth may aid autism research

by  /  13 November 2013

Cells extracted from baby teeth, which fall out on their own, may be better suited than skin cells for making induced neurons to use in autism research, suggests a study published 3 October in PLoS One.

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October 2013

Gene screen reveals altered chemical tags in autism brains

by  /  14 October 2013

One of the largest genome-wide screens of methyl tags in postmortem brains has found that people with autism have three unique regions of methylation — chemical modifications that affect gene expression. The results were reported 3 September in Molecular Psychiatry.

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