Deleting FMR1, the gene mutated in fragile X syndrome, in subsets of mouse neurons leads to distinct features of the condition.
Spectrum: Autism Research News
Problems with social interactions stem from faulty wiring of a single circuit spanning distant brain regions, results from three mouse models of autism suggest.
Differences in brain structure may distinguish boys with relatively mild features of fragile X syndrome from those with a severe form of the condition.
In people with fragile X syndrome, autism is often accompanied by seizures, trouble falling or staying asleep and anxiety.
A cannabis gel may ease features of fragile X syndrome, omega fatty acids show promise for autism in two trials, and oxytocin reinforces social behaviors through the brain’s reward pathway.
Mice missing FMR1, the gene mutated in fragile X syndrome, have an atypical brain response to meeting an unfamiliar mouse.
Many adolescents with autism experience catatonia, a quantifiable decline in motor ability.
Families need more support from researchers in order for their heroic efforts to be optimally effective.
Autism researchers’ top priority should be shifting their focus to finding treatments for severe forms of the condition.