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Spectrum: Autism Research News

Tag: FMR1

November 2017
lab mice

Fragile X behaviors may stem from gene’s loss in specific cells

by  /  13 November 2017

Deleting FMR1, the gene mutated in fragile X syndrome, in subsets of mouse neurons leads to distinct features of the condition.

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mouse with a sensor connected to brain

Three autism mouse models marked by defects in same circuit

by  /  8 November 2017

Problems with social interactions stem from faulty wiring of a single circuit spanning distant brain regions, results from three mouse models of autism suggest.

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October 2017
Brain scans of boys with fragile X syndrome fall into distinct groupings.

Brain scans reveal subtypes of fragile X syndrome in boys

by  /  30 October 2017

Differences in brain structure may distinguish boys with relatively mild features of fragile X syndrome from those with a severe form of the condition.

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A room with two twin beds. A person sitting in one and a sheep sitting in the other.

Autism in fragile X syndrome tied to seizures, sleep problems

by  /  25 October 2017

In people with fragile X syndrome, autism is often accompanied by seizures, trouble falling or staying asleep and anxiety.

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Week of OctoberOct
2nd
2017

Cannabis candidate; omega add-on; oxytocin control and more

by  /  6 October 2017

A cannabis gel may ease features of fragile X syndrome, omega fatty acids show promise for autism in two trials, and oxytocin reinforces social behaviors through the brain’s reward pathway.

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August 2017
Three white mice.

Social interactions shape gene expression in fragile X mice

by  /  16 August 2017

Mice missing FMR1, the gene mutated in fragile X syndrome, have an atypical brain response to meeting an unfamiliar mouse.

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Tendency to ‘freeze’ may be measurable feature of autism

by ,  /  1 August 2017

Many adolescents with autism experience catatonia, a quantifiable decline in motor ability.

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July 2017

Diabetes drug eases fragile X features in mice

by  /  3 July 2017

A drug used to treat type 2 diabetes reverses behavioral and brain abnormalities in a mouse model of fragile X syndrome.

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June 2017

Family groups play key role in advancing autism research

by  /  27 June 2017

Families need more support from researchers in order for their heroic efforts to be optimally effective.

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Why it’s time to spin autism genes into drug screens

by  /  27 June 2017

Autism researchers’ top priority should be shifting their focus to finding treatments for severe forms of the condition.

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