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Spectrum: Autism Research News

Tag: FMR1

August 2015

‘Sticky-flares’ give RNA traffic reports for living cells

by  /  5 August 2015

Glowing particles called ‘Sticky-flares’ can light up RNAs, the molecular blueprints for protein production, in living cells. Using these flares, researchers can plot the paths of specific RNAs through a cell.

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June 2015

Enzyme’s discovery points to new approach for fragile X

by  /  16 June 2015

Researchers have discovered an enzyme that lowers brain levels of FMRP, the protein missing in people with fragile X syndrome. Blocking the enzyme may ease fragile X symptoms in people with the disorder who have low levels of FMRP and mild symptoms.

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March 2015

Treatment eases fragile X symptoms in flies, mice

by  /  9 March 2015

Blocking an enzyme involved in learning and memory corrects brain abnormalities and improves memory in fly and mouse models of fragile X syndrome.

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Week of MarchMar
2nd
2015

Spotted: Bigger brains; dress debate

by  /  6 March 2015

A human gene gives mice bigger brains, and people with autism weigh in on that white or blue dress.

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November 2014

Exposure to ‘auntie’ mouse is therapeutic for fragile X mice

by  /  25 November 2014

A setup that mimics early behavioral intervention reverses social and cognitive deficits seen in a mouse model of fragile X syndrome.

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Diabetes drug is sweet cure for fragile X in fruit flies

by  /  19 November 2014

The memory and sleep troubles that accompany fragile X syndrome originate in a glitch in insulin signaling, suggests an unpublished study of fruit flies presented today at the 2014 Society for Neuroscience annual meeting in Washington, D.C. The study points to a widely available diabetes treatment for the syndrome.

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Non-starring cells may be key in fragile X syndrome

by  /  17 November 2014

Mice missing the FMR1 gene only in star-shaped brain cells called astrocytes recapitulate key features of fragile X syndrome. Researchers presented the unpublished results today at the 2014 Society for Neuroscience annual meeting in Washington, D.C.

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October 2014

Web of genes may hold clues for autism treatments

by  /  20 October 2014

Many of the genes that have emerged as the strongest autism candidates have turned out to regulate the expression of hundreds, if not thousands, of other genes. Within these networks, scientists are homing in on pathways that underlie autism.

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Analysis of mouse brains maps subgroups of autism

by  /  13 October 2014

A brain imaging study of 26 mouse models of autism reveals a broad range of structural abnormalities. The models cluster into groups with similar features, reports a study published 9 September in Molecular Psychiatry.

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September 2014

New algorithm detects DNA insertions and deletions

by  /  10 September 2014

A new algorithm accurately detects large DNA insertions and deletions in the protein-coding regions of the genome.

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