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Spectrum: Autism Research News


November 2017
magnetic stimulation of human brain

Magnetic stimulation bares imbalance of activity in fragile X brains

by  /  14 November 2017

Researchers have used transcranial magnetic stimulation to show that people with fragile X syndrome have weak ‘inhibitory’ signals, those that dampen neuronal activity in the brain.

white lab rat

‘Fragile’ behaviors mar studies of popular autism mouse model

by  /  13 November 2017

Researchers should proceed with caution when studying the behavior of one of the most popular mouse models of autism: the fragile X mouse model.

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lab mice

Fragile X behaviors may stem from gene’s loss in specific cells

by  /  13 November 2017

Deleting FMR1, the gene mutated in fragile X syndrome, in subsets of mouse neurons leads to distinct features of the condition.

September 2017
Illustration of Protein factories at neuronal junctions

Protein factories at neuronal junctions take center stage in autism

by ,  /  12 September 2017

Some genes linked to autism regulate the production of proteins at neuronal junctions, suggesting that disrupted protein synthesis contributes to the condition.

March 2017
illustration of person with autism struggling with addiction

Autism’s hidden habit

by  /  1 March 2017

Conventional wisdom holds that people with autism don’t get hooked on alcohol or other drugs, but new evidence suggests otherwise.

February 2017
Several arrows have fallen short of their target, which is a pill on a bullseye. This image suggests that a drug targeted towards autism's symptoms has not yet been made.

Why don’t we have better drugs for autism?

by  /  15 February 2017

Clinical trials for autism drugs have been plagued with problems: bad design, the wrong measures, too broad a range of participants. All that is finally starting to change.

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November 2016

Despite setbacks, fragile X drugs file into clinical trials

by  /  30 November 2016

Our infographic displays efforts to develop treatments for fragile X syndrome. So far, none of them have passed muster in clinical trials.

September 2016

Glowing cells bolster search for fragile X drugs

by  /  2 September 2016

A new genetic trick allows researchers to quickly spot the most promising treatments for fragile X syndrome among thousands of candidate compounds.

July 2016

Gene-editing tool locates proteins inside brain cells

by  /  8 July 2016

The popular gene-editing tool CRISPR can tag proteins in the brain, illuminating the whereabouts of autism candidates.

May 2016

Experimental cancer drug restores memory in fragile X mice

by  /  26 May 2016

An early-stage treatment for eye cancer reverses memory problems in a mouse model of fragile X syndrome.