Mutations in GABRB3, a brain receptor linked to autism, are prevalent in severe childhood epilepsy, according to a study published 12 September in Nature.
Spectrum: Autism Research News
An enzyme that may keep RNA tangle-free as it’s translated into protein is missing in some people with schizophrenia and learning difficulties. The enzyme also cooperates with the protein missing in fragile X syndrome to bind RNA, suggesting a role in protein synthesis. That’s the upshot from two studies published in the September Nature Neuroscience.
A new online database lists the likely RNA-binding sites of more than 8,000 proteins from 289 species. Researchers debuted the resource in the 11 July issue of Nature.
Watch the complete replay of Francesca Happé discussing how autism’s constellation of symptoms may have independent biological causes. Submit your own follow-up questions.
A mild form of the fragile X mutation produces an unusual protein that may trigger fragile X-associated tremor/ataxia syndrome, a neurodegenerative disorder, according to a study published 8 May in Neuron.
Researchers have uncovered a new role for the protein missing in fragile X syndrome — it regulates the release of neurotransmitters, chemical messengers in the brain, according to a mouse study published 20 February in Neuron.