People with autism who carry DNA variants in the same protein-coding region of a gene have more similar cognitive abilities and behaviors than those who carry mutations in different regions of the same gene.
Spectrum: Autism Research News
Tag: gene expression
Researchers have devised a new way of seeing how gene mutations affect cells during development.
Researchers expand on the already enormous progress made on the Human Proteome Project
Many people with mutations in the NCKAP1 gene have autism or autism traits, according to a new study spanning seven countries.
A new study pinpoints the genes and cell types that may underlie the atypical brain structure seen in people with genetic conditions linked to autism.
Researchers expand a massive repository of data on gene activity in people to show differences between males and females.
On 18 November, Donna Werling spoke about gene-expression patterns in the brains of autistic people, with an emphasis on neurobiology and sex differences.
A gene-editing treatment shows long-lasting effects in a mouse model of Angelman syndrome, a genetic condition related to autism.
An analysis of four molecular datasets shows a distinct signature, including changes in gene expression and chemical DNA modifications, in some autism brains.
People with particularly low levels of FMRP, the protein lacking in those with fragile X syndrome, are more likely to also have autism and severe intellectual disability.