The overproduction of proteins in brain cells called microglia causes social impairments, cognitive deficits and repetitive behavior in male mice, a new study has found.
Spectrum: Autism Research News
Tag: gene expression
Many genes in a brain region implicated in autism change expression patterns in late fetal development, depending on differences in neighboring DNA.
A comprehensive atlas of gene expression by brain region could spur new research on autism.
Genes involved in the formation of myelin, a fatty substance that sheathes neurons, are altered in autistic people and in several mouse models.
Rare mutations in a gene called BAZ2B are associated with various conditions of brain development, including autism.
Researchers have monitored the active genome in brain organoids over the course of nearly two years — and may find clues to autism’s roots.
A shortage of CUL3, a leading autism gene, may impair social behavior in mice by ramping up protein production in neurons.
A new technique uses ultrasound instead of light to detect gene expression in cells.