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Spectrum: Autism Research News

Tag: gene networks

July 2019
group of dark furred lab mice huddling together.

Mutations tied to autism may alter gut function, microbiome in mice

by  /  11 July 2019

Mutations in the autism gene NLGN3 may alter the gut nervous system of mice.

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June 2019
primordial soup of ancient genes and single celled organisms

Evolution of autism genes hints at their fundamental roles in body

by  /  4 June 2019

Genes associated with autism are ancient, and mutations in them have wide-ranging effects on the body, indicating their importance.

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February 2019
Portrait of Ivan Iossifov

Webinar: Ivan Iossifov discusses genetic variants linked to autism traits

27 February 2019

Watch the complete replay of Ivan Iossifov discussing the genetic basis of autism’s features.

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RNA molecules illustration

‘Editing’ of RNA may play sizeable role in autism

by  /  14 February 2019

People with autism may show scant activity in a poorly understood molecular process thought to regulate gene expression.

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January 2019
illustration shows woman under umbrella, with genes falling like rain

Expliquer la résilience à l’autisme peut faire naître de nouvelles thérapies

by  /  18 January 2019

This article is also available in anglais. Il y a quelques années la mère d’un jeune autiste m’a téléphoné. Elle venait d’apprendre que son fils, qui était dans la vingtaine, avait une délétion de SHANK3, l’un des gènes qui, d’après les découvertes de mon équipe, subit une mutation chez certaines personnes autistes. Cette nouvelle m’a […]

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December 2018

Massive analysis refines map of autism’s genetic roots

by  /  19 December 2018

The largest genetic analysis of postmortem brain tissue to date has yielded maps of when and where genes related to autism are turned on and off throughout life.

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November 2018
Black and white images shows human neurons grafted onto a mouse brain grow over time.

Human neurons take root in living mouse brains

by  /  30 November 2018

Neurons grown from human stem cells and grafted onto the brains of live mice mature and form connections like those in the fetal human brain.

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Large group of different lab mice: white mice, black and white mice and light brown mice, all in a cage on wood chips.

Database compares protein function across dozens of mouse strains

by  /  23 November 2018

A new resource details the protein-coding portions of the genomes of 36 popular mouse strains.

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Top autism gene may rewire brain by altering expression of other genes

by  /  15 November 2018

The autism gene TBR1 controls the expression of several other candidate genes that govern the architecture of the brain’s outer section.

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October 2018
Illustration of human brain in brackets suggesting circuit alterations that is associated with certain genetic mutations.

Brain scans of sleeping mice hint at subtypes of autism

by  /  9 October 2018

Mapping the effects of autism mutations on mouse brain circuits may reveal subtypes of the condition in people.

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