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Spectrum: Autism Research News

Tag: genes

August 2021
Illustration of brain showing overexcited and underexcited parts of the brain represented by jagged and loose squiggles.

Disruptions to brain’s ‘thermostat’ may underpin autism traits

by  /  18 August 2021

Mounting evidence suggests that autism often involves upsets in homeostatic plasticity, a set of processes neurons use to stabilize their activity. These disruptions result from a range of autism-linked mutations and may help to explain the condition’s famed heterogeneity.

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April 2021

Loss of CHD8 from cerebellum disrupts movements, not social behaviors

by  /  26 April 2021

Deleting the autism-linked gene CHD8 from specific cells in the cerebellum, a brain region important for movement, leads to motor deficits but does not alter social behaviors in mice.

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