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Spectrum: Autism Research News

Tag: hippocampus

March 2015

Treatment eases fragile X symptoms in flies, mice

by  /  9 March 2015

Blocking an enzyme involved in learning and memory corrects brain abnormalities and improves memory in fly and mouse models of fragile X syndrome.

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December 2014

‘Brain-normalizing’ therapy points to new kind of biomarker

by  /  1 December 2014

Pivotal response treatment, an effective form of behavioral therapy for autism, normalizes brain activity in children with the disorder, according to a small study published earlier this month in Brain Imaging and Behavior. This suggests that brain imaging can signal early responses to autism treatments.

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November 2014

Exposure to ‘auntie’ mouse is therapeutic for fragile X mice

by  /  25 November 2014

A setup that mimics early behavioral intervention reverses social and cognitive deficits seen in a mouse model of fragile X syndrome.

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Social hormone primes neurons needed to remember friends

by  /  18 November 2014

Oxytocin may influence social behavior by priming brain circuits in a region of the hippocampus important for social memory, according to preliminary results presented yesterday at the 2014 Society for Neuroscience annual meeting in Washington, D.C.

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Family of autism-linked proteins helps neurons communicate

by  /  16 November 2014

The SHANK family of proteins, some of which are strong autism candidates, work together to facilitate brain signaling, according to unpublished results presented yesterday at the 2014 Society for Neuroscience annual meeting in Washington, D.C.

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October 2014

Seizures trigger autism-like behaviors in mice

by  /  23 October 2014

Mice with an extra copy of the autism-linked gene UBE3A show abnormal social behavior after experiencing recurrent seizures. The findings, presented Tuesday at the Autism Consortium Research Symposium in Boston, provide one possible explanation for why seizures and autism often go hand in hand.

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New resource catalogs impact of DNA variants on brain

by  /  22 October 2014

A new online database called Braineac details how variations in DNA sequence shape gene expression in the human brain.

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Analysis of mouse brains maps subgroups of autism

by  /  13 October 2014

A brain imaging study of 26 mouse models of autism reveals a broad range of structural abnormalities. The models cluster into groups with similar features, reports a study published 9 September in Molecular Psychiatry.

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May 2014

Misdirected neurons may underlie autism symptoms

by  /  13 May 2014

Proteins that help guide neurons to their correct destination in the brain may be involved in autism, says Christopher Cowan.

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April 2014

Molecular mechanisms: Mutant mice seek out social contact

by  /  29 April 2014

Male mice that carry a specific mutation in the autism-linked PTEN gene have enlarged brains and show heightened interest in other mice, according to a study published 7 February in Human Molecular Genetics.

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