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Spectrum: Autism Research News

Tag: hippocampus

September 2013

Normalizing protein level preempts Angelman symptoms

by  /  9 September 2013

Depleting excess levels of a molecule involved in neuronal signaling prevents the cognitive and motor symptoms of Angelman syndrome in a mouse model of the disorder, according to a report published 15 August in Cell Reports.
 

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August 2013

Molecular mechanisms: Autism gene establishes brain links

by  /  27 August 2013

The autism-linked protein MET is expressed at the junctions between neurons during early brain development in mice, suggesting that it helps establish the connections, according to a study published 21 June in The Journal of Comparative Neurology.

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Genetics: Genes near Williams region linked to autism traits

by  /  23 August 2013

Genes near the chromosomal region implicated in Williams syndrome are involved in epilepsy and autism-like behaviors, according to a study published 12 June in the European Journal of Human Genetics.

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Large study links autism to autoimmune disease in mothers

by  /  22 August 2013

About one in ten women who have a child with autism have immune molecules in their bloodstream that react with proteins in the brain, according to a study published 20 August in Molecular Psychiatry.

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June 2013

Amygdala and autism’s checkered history

by  /  4 June 2013

To understand the amygdala’s role in autism, researchers should study its connections with other brain structures and explore its role in development, says Ralph Adolphs.

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March 2013

Fragile X mutation may lead to noisy brain signals

by  /  28 March 2013

Researchers have uncovered a new role for the protein missing in fragile X syndrome — it regulates the release of neurotransmitters, chemical messengers in the brain, according to a mouse study published 20 February in Neuron.

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February 2013

Cognition and behavior: Neurobeachin loss mimics autism

by  /  8 February 2013

Mice missing one copy of neurobeachin, an autism-linked gene that fine-tunes signals at neuronal junctions, show autism-like behaviors, according to a study set to be published in the March issue of Neurobiology of Disease.

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January 2013

Alzheimer’s drug aids autism mouse model

by  /  23 January 2013

Memantine, a drug used to treat Alzheimer’s disease, can reverse autism-like features in mice lacking one copy of the MEF2C gene, according to a poster presented last week at the Salk Institute, Fondation IPSEN and Nature Symposium on Biological Complexity in La Jolla, California.

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December 2012

Autism-linked protein sets pace for brain development

by  /  10 December 2012

Mutations in SYNGAP1, which are associated with severe intellectual disability and an increased risk of autism, do damage by speeding up the rate at which neuronal connections mature, according to a mouse study published 9 November in Cell.

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October 2012

Technique follows calcium trail to track changes in signaling

by  /  24 October 2012

Researchers have genetically engineered neurons to fluoresce in response to the calcium signals emitted when they fire, according to a study published 18 October in Neuron.

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