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Spectrum: Autism Research News

Tag: intellectual disability

January 2021
neurons in mice

Sensory perception, cell signals disrupted in people and mice missing autism gene

by  /  13 January 2021

People and mice with only one working copy of the autism gene SYNGAP1 may have trouble processing sights and sounds.

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December 2020
Micrograph of nerve cells being targeted by CRISPR enzyme to activate the silenced gene in Angelman syndrome

Hot topics in autism research, 2020

23 December 2020

The Spectrum team highlights five topics that distinguished autism research in 2020: diversity in data, gene therapies, subtyping, social circuitry and the ‘autism gene’ debate.

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Stylized DNA molecule

Mutations in the same exon linked to similar autism traits

by  /  17 December 2020

People with autism who carry DNA variants in the same protein-coding region of a gene have more similar cognitive abilities and behaviors than those who carry mutations in different regions of the same gene.

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Depressed teenager sitting on floor in darkened hallway.

Co-occurring psychiatric conditions put autistic people at risk for self-harm

by  /  11 December 2020

Autistic people are at an increased risk for intentional self-harm and death by suicide, but co-occurring psychiatric conditions may drive those behaviors.

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Paper DNA with one torn base to signify a point mutation.

Analysis links 98 genes to neurodevelopmental conditions

by  /  10 December 2020

Genetic sequences from nearly 53,000 people with autism, developmental delay or intellectual disability reveal strong ties to 98 genes.

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Cells transporting NCKAP1 protein in and out of nucleus

Rare variants tied to neuronal migration, autism traits

by  /  4 December 2020

Many people with mutations in the NCKAP1 gene have autism or autism traits, according to a new study spanning seven countries.

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November 2020
MRIs show changes over time

Big brain may mark subtype of autism

by  /  27 November 2020

Autistic boys with large brains in early childhood still have large brains in adolescence, challenging the long-standing idea that brain enlargement in autism is temporary.

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SYNGAP1 protein between neurons.

Reactions from the 2020 SYNGAP1 Scientific Conference

by  /  25 November 2020

Spectrum is covering the 2020 International SYNGAP1 Scientific Conference, which took place virtually because of the coronavirus pandemic. Here we’re highlighting researchers’ reactions to noteworthy presentations.

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Mother affectionately hugging young son.

Inheritance plays different roles in autism with and without intellectual disability

by  /  19 November 2020

Autism with intellectual disability is less heritable than autism alone, according to a new study of how the conditions run in extended families.

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Test gauges autistic children’s verbal abilities in natural settings

by  /  18 November 2020

An interactive assessment allows clinicians and researchers to evaluate an autistic child’s use of language in everyday social situations.

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