Overexpressing genes involved in the pathway, which regulates protein quality, changes repetitive behaviors in the animals.
Spectrum: Autism Research News
Cortical organoids that contain non-neuronal brain cells called microglia may reflect human neurodevelopment more faithfully than those that don’t.
Treatments that counteract the effects of an SCN2A mutation in mice increase the animals’ sociability in adulthood, according to a new unpublished study.
Animal models of autism rooted in exposure to maternal antibodies hint at different mechanisms.
Mock viral infections impair social memory in mice with a mutation tied to autism, and autistic boys are more likely than their non-autistic peers to have had serious infections early in life.
An autism-linked mutation could make the brain grow unusually large by prompting cells to express a chemical signal better known for its connection to cancer.
Misaligned gene expression maps suggest that some autism-linked genes play distinct roles in mouse and human brains.
The overproduction of proteins in brain cells called microglia causes social impairments, cognitive deficits and repetitive behavior in male mice, a new study has found.
A new technique allows researchers to transplant human microglia into mouse brains and better study the association between these cells and autism.