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Spectrum: Autism Research News

Tag: microglia

September 2021
A concerned man holds his toddler close

Severe infection may raise odds of autism in some children

by  /  17 September 2021

Mock viral infections impair social memory in mice with a mutation tied to autism, and autistic boys are more likely than their non-autistic peers to have had serious infections early in life.

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May 2021
Microglia activity seen in red, green and blue.

Autism mutation may cause big brain via ‘don’t eat me’ signals

by  /  17 May 2021

An autism-linked mutation could make the brain grow unusually large by prompting cells to express a chemical signal better known for its connection to cancer.

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February 2021
Oligodendrocyte gene grouping showing network of blue lines connecting the gene names on reddish bubbles.

Differing gene functions across species may pose problems for autism models

by  /  22 February 2021

Misaligned gene expression maps suggest that some autism-linked genes play distinct roles in mouse and human brains.

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July 2020
Man working from home office.

INSAR 2020, from home

by  /  31 July 2020

Like so many other events this year, autism’s biggest annual conference — the International Society for Autism Research meeting — was forced to go virtual because of the coronavirus pandemic.

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May 2020

Extra proteins alter microglia and behavior in mice

by  /  29 May 2020

The overproduction of proteins in brain cells called microglia causes social impairments, cognitive deficits and repetitive behavior in male mice, a new study has found.

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November 2019
Micrograph of mouse brain showing transplanted human microglia

Chimeric mouse model aids study of brain’s immune cells

by  /  15 November 2019

A new technique allows researchers to transplant human microglia into mouse brains and better study the association between these cells and autism.

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September 2019
colorful clusters of cells

Atlas of developing brain reveals rainbow of cell types

by  /  20 September 2019

An online resource reveals all major cell types in the developing human brain during the period in which autism is thought to arise.

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May 2019
Individual cells from the brains of autistic people show distinct gene-expression patterns, and are shown in different colors.

Analysis of single cells implicates set of neurons in autism

by  /  22 May 2019

A set of neurons involved in complex cognitive functions may play a central role in autism.

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neurons in mice brains

Inflammation may wield sex-specific effects on developing brain

by  /  8 May 2019

Exposure to inflammation in the womb may affect the brain and behavior of males and females differently.

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December 2018

Massive analysis refines map of autism’s genetic roots

by  /  19 December 2018

The largest genetic analysis of postmortem brain tissue to date has yielded maps of when and where genes related to autism are turned on and off throughout life.

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