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Spectrum: Autism Research News

Tag: microglia

September 2019
colorful clusters of cells

Atlas of developing brain reveals rainbow of cell types

by  /  20 September 2019

An online resource reveals all major cell types in the developing human brain during the period in which autism is thought to arise.

May 2019
Individual cells from the brains of autistic people show distinct gene-expression patterns, and are shown in different colors.

Analysis of single cells implicates set of neurons in autism

by  /  22 May 2019

A set of neurons involved in complex cognitive functions may play a central role in autism.

neurons in mice brains

Inflammation may wield sex-specific effects on developing brain

by  /  8 May 2019

Exposure to inflammation in the womb may affect the brain and behavior of males and females differently.

December 2018

Massive analysis refines map of autism’s genetic roots

by  /  19 December 2018

The largest genetic analysis of postmortem brain tissue to date has yielded maps of when and where genes related to autism are turned on and off throughout life.

November 2018

Neuron tag may shield synapses from brain’s pruning shears

by  /  12 November 2018

A protective molecular tag on neurons can prevent microglia, the brain’s immune cells, from trimming away their connections with other neurons.


Inflammation in womb may spawn autism-like traits in males

by  /  6 November 2018

Chronic exposure to inflammation in the womb alters autism gene expression and disrupts social behavior in male mice, but not females.


Postmortem brain study hints at cell types involved in autism

by  /  5 November 2018

An unprecedented look at gene expression in tens of thousands of brain cells from autistic people suggests important roles in the condition for a neuronal subtype and for microglia.


Brain’s immune cells may underlie autism risk from maternal infection

by  /  4 November 2018

A pregnant mouse’s response to infection alters the immune cells in her pups’ brains, and this may contribute to their autism-like behaviors.

September 2018

Autism’s sex bias may originate in brain’s immune cells

by  /  5 September 2018

The brain’s immune cells, called microglia, function differently in male and female rodents. In people, a similar phenomenon may make male brains more vulnerable to autism.


Charting one cell at a time, scientists reveal brain’s vast diversity

by  /  3 September 2018

How many cell types does the brain contain? Two new mouse studies bring scientists closer to the answer.