Microglia may have only small appetite for synapses
Microglia come into frequent contact with synapses, the connections between neurons, but they appear to nibble on them rather than engulf and digest them.
Microglia come into frequent contact with synapses, the connections between neurons, but they appear to nibble on them rather than engulf and digest them.
Women describe relief at finally learning they have autism, a man with epilepsy narrates during stimulation of his brain, and the brain’s immune cells are caught on film nibbling at neuronal connections.
Autism parents fall for the marketing of essential oils, the pruning hypothesis of brain development matures, and an online manual classifies mouse behavior.
Gene expression patterns in the brains of people with autism are similar to those of people who have schizophrenia or bipolar disorder.
Researchers have mapped how immune cells in the brain called microglia change with age in mice.
Mouse pups exposed to an immune response in the womb show autism-like behaviors and altered gene expression in brain cells called microglia.
Immune cells in the brain called microglia play diverse roles in the mouse embryo but assume a common function by adolescence.
Some genes linked to autism regulate the production of proteins at neuronal junctions, suggesting that disrupted protein synthesis contributes to the condition.
A trial of umbilical cord blood as a treatment for autism has passed a critical safety test, but many researchers remain skeptical of the approach.
A boost in the activity of microglia, the brain’s immune cells, during gestation may predispose boys to autism.