Researchers have mapped how immune cells in the brain called microglia change with age in mice.
Spectrum: Autism Research News
Mouse pups exposed to an immune response in the womb show autism-like behaviors and altered gene expression in brain cells called microglia.
Immune cells in the brain called microglia play diverse roles in the mouse embryo but assume a common function by adolescence.
Some genes linked to autism regulate the production of proteins at neuronal junctions, suggesting that disrupted protein synthesis contributes to the condition.
A trial of umbilical cord blood as a treatment for autism has passed a critical safety test, but many researchers remain skeptical of the approach.
A boost in the activity of microglia, the brain’s immune cells, during gestation may predispose boys to autism.
The brains of people with autism show a distinct molecular signature that reflects alterations in how genes are pieced together and expressed.