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Spectrum: Autism Research News

Tag: microglia

October 2015
Week of SeptemberSep
28th
2015

Power player; placebo predictors

by  /  2 October 2015

The MacArthur Foundation honors neuroscientist Beth Stevens, and researchers pin down factors that influence the placebo effect in autism trials.

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September 2015
Portrait of Beth Stevens.

Beth Stevens: Casting immune cells as brain sculptors

by  /  24 September 2015

Beth Stevens is unmasking new roles for microglia, the mysterious brain cells that seem to shape brain circuits.

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May 2015

Study questions promise of bone marrow transplant for Rett

by  /  22 May 2015

Researchers from four labs were unable to reproduce the findings from a high-profile 2012 study in which bone marrow transplants dramatically extended the lives of mice with features of Rett syndrome. Their sobering findings were published yesterday in Nature.

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April 2015

Rett mutation may lead to runaway inflammation

by  /  30 April 2015

The mutation that causes Rett syndrome may spark uncontrolled inflammation throughout the body and brain, suggests a study published last week. The findings may explain the syndrome’s wide range of symptoms, from seizures to gut problems.

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December 2014

Postmortem brains point to molecular signature of autism

by  /  22 December 2014

An analysis of genes expressed in the postmortem brains of people with autism has identified three molecular pathways linked to the disorder. The findings, published 10 December in Nature Communications, add to mounting evidence that the myriad causes of autism converge on common biological processes.

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November 2014

Mouse study sheds light on maternal infection, autism link

by  /  21 November 2014

A new study points to a possible link between inflammation in the womb, brain overgrowth and the behavioral impairments seen in autism.
 

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In mouse model of Rett, immune cells overly sensitive

by  /  20 November 2014

Loss of MeCP2, the Rett syndrome gene, depletes immune cells throughout the bodies of mice, researchers reported yesterday at the 2014 Society for Neuroscience annual meeting in Washington, D.C.

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The next hot topic in autism research? Immune cells

by  /  16 November 2014

Some cases of autism may result from glitches in immune cells in the blood: This provocative idea stems from a series of unpublished mouse studies presented yesterday at the 2014 Society for Neuroscience annual meeting in Washington, D.C.

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March 2014

Molecular mechanisms: Star-shaped cells abound in autism

by  /  18 March 2014

Brains from people with autism have more support cells called glia and fewer neurons than do control brains, suggests a study published 10 January in Molecular Autism.

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February 2014

Gene expression implicates inhibitory neurons in autism

by  /  26 February 2014

By matching the genes expressed in particular cell types with those linked to a disorder, researchers may be able to identify the cell types implicated in the disorder, they report in a study published 22 January in the Journal of Neuroscience. They use this method to link interneurons and immune cells to autism.

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