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Spectrum: Autism Research News

Tag: microglia

February 2014

Scarcity of brain’s immune cells alters mouse behavior

by  /  13 February 2014

A temporary shortage of microglia — immune cells in the brain that prune unnecessary neural connections — in infancy can have long-lasting effects on brain circuits and behavior, according to a study published in Nature Neuroscience on 2 February.

November 2013

Study spells caution for bone marrow transplants for Rett

by  /  12 November 2013

Bone marrow transplants, which have been shown to arrest symptoms of Rett syndrome in young mice, have little effect on older mice, according to preliminary results presented Monday at the 2013 Society for Neuroscience annual meeting in San Diego. The findings suggest that this approach may not be a viable treatment for those who already have symptoms of the disorder.


Brain’s immune cells boost rapid transmission of signals

by  /  11 November 2013

Two new studies bolster the emerging idea that microglia, cells that were long dismissed as passive soldiers of the brain’s immune system, are in fact actively involved in shoring up connections between neurons. The unpublished work was presented Sunday at the 2013 Society for Neuroscience annual meeting in San Diego.

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Beth Stevens discusses brain immunity and wiring

20 November 2013

Watch the complete replay of Beth Stevens discussing the link between immune cells in the brain, neuronal junctions and autism. Submit follow-up questions.

September 2013

Duplication of chromosome 15 region mirrors autism

by  /  23 September 2013

People with autism and those with duplications of the 15q11-13 chromosomal region share a distinctive pattern of gene expression in the brain, according to unpublished research presented Friday at the Dup15q Alliance Scientific Meeting in Sacramento, California.

August 2013

Abnormal brain immune cells: Autism’s cause or result?

by  /  19 August 2013

Mounting evidence finds abnormally high levels of immune cells in the brains of people with autism. But how do we separate cause from effect?


Brain’s immune cells show intriguing links to autism

by  /  13 August 2013

Emerging evidence indicates that microglia, the brain’s immune cells, are altered in some individuals with autism, raising questions about their role in brain development, says Beth Stevens.

March 2013

Jonathan Kipnis on microglia and therapeutic targets

27 March 2013

Watch the complete replay of Jonathan Kipnis discussing his groundbreaking work connecting microglia and peripheral immunity to autism. Submit your own follow-up questions.


What does the brain’s immunity have to do with autism?

by  /  4 March 2013

In December, SFARI brought together a group of scientists studying the connection between microglia and autism. These scientists are trying to delineate the next steps for this emerging field. Join the conversation.

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January 2013

Brain imaging study points to microglia as autism biomarker

by  /  10 January 2013

Microglia, brain cells that are part of the immune system, are more activated in the brains of young men with autism than in controls, according to an imaging study published 26 November in the Archives of General Psychiatry.