The Spectrum team highlights five topics that distinguished autism research in 2020: diversity in data, gene therapies, subtyping, social circuitry and the ‘autism gene’ debate.
Spectrum: Autism Research News
Tag: neural circuits
Mice that model 22q11.2 deletion syndrome lack social memory, but that trait can be reversed using a drug that targets the flow of potassium ions in neurons.
Two types of neurons process social information, a new mouse study suggests, but only one is disrupted in mice missing the autism-linked gene FMR1.
Mice with mutations in the autism-linked gene SYNGAP1 have trouble sensing touch, which may stem in part from brain-circuit alterations and dulled alertness.
Autistic men show a greater imbalance between excitatory and inhibitory signaling in the brain than autistic women do, which could explain sex differences in ‘camouflaging.’
A growing number of studies are revealing circuits that may underlie social challenges in autism — and how to fine-tune them.
Hearing difficulties and autism often overlap, exacerbating autism traits and complicating diagnoses.
A new atlas lays bare how synapses, or the junctions between neurons, change from birth to old age in mice.