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Spectrum: Autism Research News

Tag: oxytocin

October 2021
Photo: A nasal spray bottle sprays upwards.

Intranasal oxytocin ineffective for autism in large trial

by  /  13 October 2021

The hormone is no better than placebo at boosting social behavior in autistic children, according to a new study, but it may still benefit a subset of people with the condition.

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September 2021
Illustration of hybrid objects: part light bulb, part lab vial, some in blue and some in red to signify null and replicated results

Null and Noteworthy: Null rejection, repetitive behaviors, unsuccessful treatments

by  /  23 September 2021

In this edition of Null and Noteworthy, tests of intranasal oxytocin and an Angelman syndrome treatment fail to see results.

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March 2021
Scanning elecgron micrograph of Faecal bacteria.

Gut microbes shape social behavior in autism mouse model

by  /  26 March 2021

Treating mice missing the autism-linked gene CNTNAP2 with a strain of gut bacteria makes them more social but no less hyperactive.

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Nasal sprayer makes a brain shape out of its spray.

How to improve oxytocin research for autism

by ,  /  9 March 2021

To guard against hype, scientists studying oxytocin’s role in autism and its potential as a treatment need to embrace robust theories, rigorous delivery methods and reproducible research practices.

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January 2021
Scans of mouse brain slices showing differences in oxytocin levels

Oxytocin alters brain activity to boost sociability in mice missing autism gene

by  /  13 January 2021

Infusions of the hormone oxytocin may make mice that model autism more social by normalizing their brain activity patterns.

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Zebrafish lacking oxytocin receptors skip school

by  /  13 January 2021

Model fish seem to spend more time swimming solo than wildtype zebrafish do, and neurochemicals in their brains respond differently to social interactions.

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two mice interacting.

Mice show brain, behavior changes weeks after oxytocin treatment

by  /  11 January 2021

Intranasal oxytocin may spur new neuron growth and changes in social behavior after a few weeks.

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December 2020
Oxytocin neurons stained pink and green.

Autism-linked gene exerts varied effects on oxytocin circuits in mice

by  /  18 December 2020

Two types of neurons process social information, a new mouse study suggests, but only one is disrupted in mice missing the autism-linked gene FMR1.

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August 2020
Two mice side-by-side.

Drug improves social behaviors, oxytocin signaling in autism mouse model

by  /  31 August 2020

Mice missing the autism gene NLGN3 have altered social behaviors and brain responses to the hormone oxytocin, both of which improve after treatment with a drug that helps regulate protein production.

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July 2020
Man working from home office.

INSAR 2020, from home

by  /  31 July 2020

Like so many other events this year, autism’s biggest annual conference — the International Society for Autism Research meeting — was forced to go virtual because of the coronavirus pandemic.

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