Mice missing the autism-linked gene SHANK3 use more neurons to engage in social behavior than control mice do, reflecting a more disorganized, less efficient brain signaling network.
Spectrum: Autism Research News
Tag: prefrontal cortex
A subset of brain cells signal when someone tries to infer another person’s thoughts, according to a new study.
A glowing protein tracks serotonin levels and location in the brains of living mice and could yield clues to the neurotransmitter’s role in autism.
Mutations in two genes linked to autism and intellectual disability boost the immune response and cause synapse dysfunction.
People with autism or autism traits may be especially vulnerable to brain aging and cognitive decline, two studies suggest.
A set of neurons connecting the prefrontal cortex and the thalamus helps regulate social interactions in mice.
Autistic men show a greater imbalance between excitatory and inhibitory signaling in the brain than autistic women do, which could explain sex differences in ‘camouflaging.’
A growing number of studies are revealing circuits that may underlie social challenges in autism — and how to fine-tune them.
The amygdala has long been a focus of autism research. But its exact role in the condition has been unclear.
Many genes in a brain region implicated in autism change expression patterns in late fetal development, depending on differences in neighboring DNA.