Skip to main content

Spectrum: Autism Research News

Tag: rapamycin

August 2021

Molecular overlap links tuberous sclerosis, fragile X

by  /  16 August 2021

Brain cells from the cerebellums of mice that model tuberous sclerosis show dampened levels of proteins controlled by FMRP, the protein missing in fragile X syndrome.

0 Comments
March 2020
Illustration showing the human brain with neurons made out of flower shapes and the cerebellum highlighted in gold and yellow.

Brain’s motor hub plays unsung role in social skills, cognition

by  /  9 March 2020

Long known as the director of movement, the cerebellum may also coordinate social and cognitive abilities, including those central to autism.

0 Comments
November 2019

Mouse study reveals overlooked target for autism therapies

by  /  20 November 2019

Blocking one form of an enzyme implicated in autism eases unusual behaviors and seizures in mice missing a top autism gene.

0 Comments
September 2019
row of babies playing with toys that look like genome sequence

Studies of tuberous sclerosis may shed light on biology of autism

by  /  24 September 2019

Tuberous sclerosis provides a unique opportunity to understand autism because about half of people with that single-gene condition also have autism.

0 Comments
August 2018
Two scientists standing in a lab.

Family ties: Sabatini brothers crack codes that may underlie autism

by  /  30 August 2018

David and Bernardo Sabatini, brothers born just a year and a half year apart, invent their way to answering big questions about autism.

0 Comments
January 2018
group of rats on wood chips

Drug in trials for one autism-linked condition may worsen another

by  /  26 January 2018

The drug rapamycin, which is in clinical trials as a treatment for tuberous sclerosis, may exacerbate features of fragile X syndrome, another condition related to autism.

0 Comments
November 2017
Mice missing the tuberous sclerosis gene in astrocytes have frequent seizures.

Cancer drug wards off seizures in mouse model of tuberous sclerosis

by  /  13 November 2017

A drug called rapamycin prevents seizures in a mouse model of the autism-related condition tuberous sclerosis complex.

2 Comments
January 2017
A surreal portrait of doctors walking out on vibrant tree-limbs, as it were. This represents doctors exploring novel pathways in cancer research.

The curious connection between autism and cancer

by  /  11 January 2017

A surprising number of genes associated with autism also have links to cancer. Does that mean cancer drugs can treat autism?

0 Comments
May 2016
Illustration shows doctors in Libya looking at a city, with children standing in the foreground.

The gene hunters

by  /  18 May 2016

Criss-crossing the globe on a quest for unusual DNA, researchers have discovered a rare mutation that promises insights into both epilepsy and autism — and points to a treatment.

1 Comment
November 2014

Treatment prevents autism-like symptoms in ‘teenage’ mice

by  /  16 November 2014

A treatment that targets the genetic defect in tuberous sclerosis prevents autism-like symptoms in mice at 6 weeks of age — the mouse equivalent of adolescence. Researchers presented the unpublished results yesterday at the 2014 Society for Neuroscience annual meeting in Washington, D.C.
 

1 Comment