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Spectrum: Autism Research News

Tag: Rett syndrome

October 2015

Differences between rodents show limitations of models

by  /  20 October 2015

The same autism-linked mutation can lead to dramatically different behaviors in rats and mice.

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Of mice and women

by  /  19 October 2015

A new government mandate requires researchers to include females in their animal studies — or explain why they don’t. What will this mean for autism research?

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Drug rescues learning deficits in Rett syndrome mouse

by  /  18 October 2015

A new drug that targets a molecule involved in learning reverses some cognitive difficulties in a mouse model of Rett syndrome.

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Excitatory neurons may underlie some aspects of Rett syndrome

by  /  17 October 2015

Mice that lack the Rett gene in a subset of neurons that activate neural circuits develop tremor and anxiety-like behaviors, two characteristics of the syndrome.

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Study grants starring role to astrocytes in Rett syndrome

by  /  17 October 2015

A new study casts brain cells called astrocytes as minor stars in Rett syndrome, a disorder that almost exclusively affects girls.

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New methods tighten ​net​ around autism genes

by  /  9 October 2015

Autism researchers are sharpening their statistical tools to make sense of the growing pool of autism genes.

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Dispatches from ASHG 2015

by  /  9 October 2015

These short reports from our reporter, Jessica Wright, give you the inside scoop on developments at the 2015 American Society of Human Genetics Annual Meeting.

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August 2015

Webinar: Huda Zoghbi explores biology of Rett syndrome

30 September 2015

Watch the complete replay of Huda Zoghbi discussing the genetics and molecular biology of Rett syndrome, an autism-like neurodevelopmental disorder.

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Blinking mice bolster cerebellum’s link to autism

by  /  14 August 2015

Mice carrying any one of five autism-linked mutations struggle to associate a flash of light with an irritating puff of air. The findings suggest that the mice have trouble integrating information from multiple senses — a skill governed by the cerebellum.

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July 2015

Lab-spun spheres reveal common biology in boys with autism

by  /  16 July 2015

Balls of neurons derived from skin cells of four boys with autism show shared alterations in biology and gene expression, researchers reported today in Cell. The findings finger FOXG1, a gene involved in brain development, as a player in autism.

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