The same autism-linked mutation can lead to dramatically different behaviors in rats and mice.
Spectrum: Autism Research News
Tag: Rett syndrome
A new drug that targets a molecule involved in learning reverses some cognitive difficulties in a mouse model of Rett syndrome.
Mice that lack the Rett gene in a subset of neurons that activate neural circuits develop tremor and anxiety-like behaviors, two characteristics of the syndrome.
A new study casts brain cells called astrocytes as minor stars in Rett syndrome, a disorder that almost exclusively affects girls.
Watch the complete replay of Huda Zoghbi discussing the genetics and molecular biology of Rett syndrome, an autism-like neurodevelopmental disorder.
Mice carrying any one of five autism-linked mutations struggle to associate a flash of light with an irritating puff of air. The findings suggest that the mice have trouble integrating information from multiple senses — a skill governed by the cerebellum.
Balls of neurons derived from skin cells of four boys with autism show shared alterations in biology and gene expression, researchers reported today in Cell. The findings finger FOXG1, a gene involved in brain development, as a player in autism.