Mutations in genes that seemingly don’t affect the corresponding proteins may still boost autism risk.
Spectrum: Autism Research News
Individuals who have autism or another psychiatric condition tend to pair up with others who share their diagnosis.
Watch the replay of Claudia Bagni’s webinar, in which she described molecular pathways that are impaired in fragile X syndrome, autism and schizophrenia. She also discussed mouse and fly models, as well as human cells.
Newborn mice missing a copy of the autism candidate gene TBX1 squeak in overly simple sequences when beckoning their mothers.
Two seemingly similar mutations in the SHANK3 gene have divergent effects on the brain and behavior.
Researchers are studying more than 1,000 postmortem brains with the goal of unearthing shared genetic roots in neuropsychiatric conditions, including autism.
Using a new genetic approach, researchers are finding shared risk factors for seemingly unrelated conditions, ranging from autism to obesity.
DNA sequences called enhancers — which boost the expression of genes from within or outside them — are enriched for genetic variants linked to autism, suggests a new study. The finding may help researchers understand how variants outside genes contribute to autism.