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Spectrum: Autism Research News

Tag: sequencing

August 2015

Control centers for genes rife with autism-linked DNA blips

by  /  3 August 2015

DNA sequences called enhancers — which boost the expression of genes from within or outside them — are enriched for genetic variants linked to autism, suggests a new study. The finding may help researchers understand how variants outside genes contribute to autism.

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July 2015

Method improves analysis of chemical tags that control genes

by  /  8 July 2015

A new strategy sharpens the analysis of chemical tags on the DNA-protein complexes that regulate gene expression. The method may help researchers decipher how gene expression goes awry in disorders such as autism.

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Week of JuneJun
29th
2015

Spotted: Sticking point; embryo ethics

by  /  3 July 2015

California might make vaccines mandatory, and religious figures may weigh in on the genetic engineering of embryos.

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June 2015
Week of JuneJun
22nd
2015

Spotted: Rebranding oxytocin; marsupial madness

by  /  26 June 2015

The ‘love hormone’ oxytocin needs a scientific makeover, and left-handed kangaroos don’t have autism.

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Body clock genes may set pace for sleep issues in autism

by  /  19 June 2015

People with autism are twice as likely to carry alterations in genes that regulate the circadian clock, or the body’s sleep-wake cycle as those without the disorder. The findings may help explain why most children with autism have trouble with sleep.

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Startled fish help sound out sensory overload in autism

by  /  8 June 2015

There is some evidence that neural habituation — the process by which neurons get used to sensory stimuli — goes awry in autism. Mutant fish may help us understand the sensory sensitivities that often accompany the disorder, says Alan Packer.

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Online atlas unravels gene activity in diverse tissues

by  /  3 June 2015

A new resource reveals that gene expression varies more across tissues in one person than it does in the same tissue type among individuals. The findings, described 8 May in Science, indicate that the brain’s gene expression signature is unique.

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Boys with autism inherit mutations from unaffected mothers

by  /  1 June 2015

Rare inherited mutations may contribute to autism in roughly 10 percent of boys with the disorder, according to a study published 11 May in Nature Genetics. These genetic glitches are primarily passed down from unaffected mothers.

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May 2015

Sex differences take center stage in autism special issue

by  /  29 May 2015

One of the most consistent findings in autism, and perhaps the most perplexing, is that it affects about four boys for every girl. This gender bias has become a hot topic in autism research — so much so that Molecular Autism devoted its entire May issue to it.

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Technique decodes gene sequence and activity in single cells

by  /  27 May 2015

A new method simultaneously reveals a single cell’s DNA sequence and which of its genes are turned on.

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