Mutations in the autism-linked gene PAX5 underlie a range of traits, including developmental delay, intellectual disability, seizures and autism.

Petrus de Vries is on a quest to outfit Africa, the continent of his birth, with trained autism researchers and service providers.

Only a quarter of more than 1,000 autism intervention studies published since 1990 report on participants’ races and ethnicities, and just one included a Native American participant.

The fact that autism seems to affect more boys than girls is often attributed to diagnostic gaps, but the skew remains largely unexplained. Some scientists are turning to basic biology for answers.

A modified version of a probe commonly used in animals detected neuronal activity across different cortical layers in three people undergoing brain surgery.

The connection is likely mediated by environmental, not genetic, factors, according to a new study.

Activating the immune system blunts social behavior in mice missing a copy of the autism-linked gene SHANK3, according to a new study. Blocking TRPV4, which encodes an ion channel involved in inflammatory responses, can reverse this effect.

A basic scientist at heart, Hollis Cline has spent decades pushing the boundaries of what researchers can see in the brain. Her persistence has led to a deeper understanding of how some autism-linked genes influence brain development.

Some copy number variants may boost a person’s chances of having autism, but to a lesser extent than previously thought.