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Tag: striatum

March 2021
A digital rendering of a green neuron on black
News

Brain activity jump-starts autism-linked genes in human neurons

by  /  5 March 2021

Some neurons activate autism-linked genes when they fire, according to a new study.

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January 2021
In cortical-striatal assembloids, striatal neurons (magenta) derived from individuals with Phelan-McDermid syndrome fire more frequently than neurons from controls.
News / Toolbox

Brain ‘assembloids’ capture circuit flaws in syndrome tied to autism

by  /  21 January 2021

Merging 3D clusters of neurons that mimic different brain regions models the atypical electrical activity seen in an autism-related condition.

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December 2020
researcher facing off with the coronavirus.
Features / Special Reports / Hindsight is 2020: The year in review

Rewind: Spectrum’s best from 2020

23 December 2020

Our staff picks the stories, podcasts and special reports that stood out from the rest this past year.

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October 2020
Illustration shows a student struggling with a classroom task.
News

How the striatum is linked to autism

by  /  9 October 2020

The repetitive behaviors seen in autism may originate in the striatum, a cluster of neurons involved with initiating and executing movements.

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April 2020
White mouse grooming
News

Gene linked to schizophrenia tied to autism-like behaviors

by  /  23 April 2020

Mice missing DLG2, a protein central to neuronal activity, are anxious, sleep poorly and overgroom themselves.

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February 2020
brain form in the shape of white flowers on black background with the striatum in red
News

Striatum, the brain’s reward hub, may drive core autism traits

by  /  17 February 2020

Associated primarily with its role in movement, the striatum may also influence the social difficulties of autistic people.

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November 2018
Delicate network of neurons and synapses.
News

Webbing around neurons altered in autism mouse models

by  /  8 November 2018

Lattice-like structures that surround neurons may be overly abundant — or scarce — in brain regions of three autism mouse models.

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September 2018
Features / Deep Dive

Rebooting Becky’s brain

by  /  12 September 2018

An electrical brain implant all but erased the obsessions that had consumed Becky Audette, years after her autism diagnosis. Could similar implants help other people with severe autism?

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August 2018
Two scientists standing in a lab.
News / Profiles

Family ties: Sabatini brothers crack codes that may underlie autism

by  /  30 August 2018

David and Bernardo Sabatini, brothers born just a year and a half year apart, invent their way to answering big questions about autism.

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July 2018
a particle of gold and a protective shell nable CRISPR to traverse safely into the brain.
News

Gene editing via nanoparticles may treat autism syndromes

by  /  5 July 2018

A miniature particle delivers the gene-editing tool CRISPR into the brains of fragile X mice.

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