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Spectrum: Autism Research News

Tag: synapses

February 2021
Oil and water with colors behind: blue, green, yellow and red.

How microscopic ‘condensates’ in cells might contribute to autism

by  /  23 February 2021

A controversial idea about how cells compartmentalize their contents into droplets — like beads of oil in water — could be key to understanding autism, says Julie Forman-Kay.

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January 2021

Two top autism genes may have a mechanism in common

by  /  13 January 2021

Mutations in two genes linked to autism and intellectual disability boost the immune response and cause synapse dysfunction.

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Proteins present at neuronal junctions.

Repeat labeling helps reveal synaptic proteins

by  /  12 January 2021

A novel microscopy technique offers the most detailed look to date at the proteins present at neuronal junctions.

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grid of clocks showing different times

Missing autism gene may affect time perception in mice

by  /  11 January 2021

Mice missing a copy of the autism-linked gene NRXN1 appear to perceive some time intervals as shorter than control mice do, according to a new study.

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November 2020
SYNGAP1 protein between neurons.

Reactions from the 2020 SYNGAP1 Scientific Conference

by  /  25 November 2020

Spectrum is covering the 2020 International SYNGAP1 Scientific Conference, which took place virtually because of the coronavirus pandemic. Here we’re highlighting researchers’ reactions to noteworthy presentations.

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August 2020
Mouse brain images show proteins in mouse brains at different ages.

New ‘synaptome’ maps neuronal connections in mouse brain across lifespan

by  /  5 August 2020

A new atlas lays bare how synapses, or the junctions between neurons, change from birth to old age in mice.

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May 2020

Extra proteins alter microglia and behavior in mice

by  /  29 May 2020

The overproduction of proteins in brain cells called microglia causes social impairments, cognitive deficits and repetitive behavior in male mice, a new study has found.

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April 2020
Two neuron images compared side by side

Lithium may treat behavior linked to autism gene

by  /  24 April 2020

The mood-stabilizing drug lithium seems to ease repetitive behaviors seen in mice missing SHANK3, an autism gene.

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Microscopic view of neurons

Mutations in autism gene linked to distinct conditions

by  /  3 April 2020

Individuals with mutations in an autism gene called TRIO may have a range of conditions, including intellectual disability and anomalous head size.

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February 2020
3D image of colorized brain sections showing neuron connections

Map of fly brain lights up millions of connections

by  /  12 February 2020

A new wiring diagram of the fruit fly brain is the most complex ever created.

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