Mock viral infections impair social memory in mice with a mutation tied to autism, and autistic boys are more likely than their non-autistic peers to have had serious infections early in life.
Spectrum: Autism Research News
Neuronal axons ignore guidance cues after a mutation in the gene TSC2 disrupts signaling through RhoA, a protein regulated by many autism-linked genes.
The overproduction of proteins in brain cells called microglia causes social impairments, cognitive deficits and repetitive behavior in male mice, a new study has found.
Tuberous sclerosis provides a unique opportunity to understand autism because about half of people with that single-gene condition also have autism.
A drug that treats tumors and epilepsy in people with tuberous sclerosis complex does not boost their intelligence or ease autism traits.
Triggering an immune defense in newborn male mice missing a copy of TSC2, a gene linked to autism, impairs the mice’s social memory.
David and Bernardo Sabatini, brothers born just a year and a half year apart, invent their way to answering big questions about autism.
Watch the complete replay of Shafali Jeste discussing her work investigating brain structure and function in infants at high risk for autism.
A checklist for fragile X syndrome could help identify people with the condition in low-resource settings, France unveils a plan for early diagnosis and education of children with autism, and virally inserted ‘bar codes’ help track individual neurons.
Mice with the mutations linked to tuberous sclerosis make too little protein in their brains — a finding that contradicts a leading theory about the condition.