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Spectrum: Autism Research News

Tag: valproic acid

July 2017
Week of JulyJul
17th
2017

Valproate ban; hearing voices; adult autism and more

by  /  21 July 2017

A movement to ban valproate during pregnancy gains a foothold in France, people with auditory hallucinations seek to demedicalize the experience, and adults on the spectrum speak out.

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April 2017
A small boy is surrounded by pills, evoking a sense that we are giving individuals on the spectrum too many psychiatric drugs.

Autism’s drug problem

by  /  19 April 2017

Many people on the spectrum take multiple medications — which can lead to serious side effects and may not even be effective.

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July 2016

Epilepsy in family members raises risk of autism

by  /  21 July 2016

A study of more than 85,000 people with epilepsy and their immediate relatives suggests that epilepsy and autism share biological roots.

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October 2015

Vasopressin blocker improves social deficits in rat autism model

by  /  19 October 2015

A drug that blocks the function of the hormone vasopressin improves social interactions and memory in rats that model autism.

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July 2015

Marmosets that miss social cues may mimic autism

by  /  29 July 2015

Marmosets exposed to an epilepsy drug in the womb do not recognize reciprocity — the social give-and-take that is a challenge for some people with autism — suggests a new study. The findings add to mounting evidence that these tiny monkeys offer clues about autism.

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November 2014

Enriched environment staves off autism-like behavior in rats

by  /  20 November 2014

Rats exposed in utero to the epilepsy drug valproic acid, a risk factor for autism, do not develop autism-like behaviors if they are reared in a stimulating environment. Researchers presented the unpublished findings yesterday at the 2014 Society for Neuroscience annual meeting in Washington, D.C.

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Tadpole model links epilepsy drug’s effects to chromatin

by  /  16 November 2014

Valproic acid, an epilepsy drug that increases the risk of autism, may alter neural circuits by opening up chromatin, a tightly packaged form of DNA in the nucleus. Researchers presented the unpublished data today at the 2014 Society for Neuroscience annual meeting in Washington, D.C.

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February 2014

Cognition and behavior: Epilepsy drug alters rodent gut

by  /  14 February 2014

In utero exposure to the epilepsy drug valproic acid, which ups the risk of autism, may alter the composition of gut bacteria in rodents, according a study published 11 December in Brain Behavior and Immunity.

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How to evaluate the ‘intense world’ paradigm?

by  /  11 February 2014

What evidence supports the idea that autism stems from overactive brain responses to sensory input? Researchers weigh in on this controversial theory.

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January 2014

Intense world theory raises intense worries

by ,  /  21 January 2014

The ‘intense world theory’ of autism, which has attracted much interest from the popular press, has received very little academic scrutiny. Uta Frith and Anna Remington ask: Is it as positive as it purports to be, and what does it mean for autism?

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