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Spectrum: Autism Research News

Tag: valproic acid

December 2013

Understanding contradictory connectivity reports in autism

by ,  /  10 December 2013

Studies at the level of neural circuits are needed to better understand the importance of both increased and decreased connectivity between different regions in the autism brain, say John Rubenstein and Vikaas Sohal.

1 Comment
November 2013

Guinea pigs enter rat race for autism models

by  /  13 November 2013

Guinea pigs have advantages over other rodent species commonly used to model disorders such as autism, according to preliminary research published Tuesday at the Society for Neuroscience annual meeting in San Diego.

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With training, autism rat models overcome hearing problems

by  /  11 November 2013

Rat models of autism have a weak and sluggish brain response to speech sounds, but behavioral training can improve their performance. The unpublished results, presented Sunday at the 2013 Society for Neuroscience annual meeting in San Diego, suggest that a similar approach may benefit people with the disorder.

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First tadpole model of autism surfaces at conference

by  /  11 November 2013

Researchers have recreated one of the most popular rodent models of autism in a decidedly slimier animal: the tadpole. The unpublished study was presented Sunday at the 2013 Society for Neuroscience annual meeting in San Diego.

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August 2013

Can epilepsy cause autism?

by  /  26 August 2013

Teasing apart the link between autism and epilepsy opens the door for a possible preventive option for some cases of autism. But is the potential worth the risks?

19 Comments
May 2013

Risky exposures

by  /  3 May 2013

Two large studies confirm that the use of antidepressants or the epilepsy drug valproate by pregnant women raises the risk of autism in their children.

2 Comments
April 2013

Molecular mechanisms: Rats could model autism gender bias

by  /  9 April 2013

Prenatal exposure of rats to the epilepsy drug valproic acid leads to behavioral and brain features that resemble autism, in males more than in females, according to a study published in the March issue of the Journal of Neurochemistry.

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February 2013

Controversial study touts blood pressure drug for autism

by  /  18 February 2013

Bumetanide, a drug that’s long been used to treat high blood pressure, modestly improves social behaviors in children with mild forms of autism, according to the results of a small trial published in December in Translational Psychiatry.

10 Comments
August 2012

Genes and environment are two-way street in autism risk

by  /  21 August 2012

Genes and the environment each influence the role of the other in determining the risk of developing autism. Genetics can determine how susceptible one is to the environment, and environmental factors can influence gene expression and introduce mutations, says immunologist Janine LaSalle.

9 Comments
June 2012

Valproate fate

by  /  5 June 2012

A new rat study shows that the precise timing of early valproate exposure, an autism risk factor, can have a big influence on behavior later in development.

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