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Spectrum: Autism Research News

Tag: vocalization

June 2012

SHANK2 mouse models show opposite brain signaling

by  /  25 June 2012

Two new strains of mice carrying different mutations in the SHANK2 gene show similar autism-like behaviors but opposing effects on brain signaling, according to two independent studies published 14 June in Nature.

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May 2012

Molecular mechanisms: Mutant mice show signs of autism

by  /  25 May 2012

Mice that are unable to produce a carbohydrate molecule that regulates cell growth show behaviors that resemble the core deficits of autism, according to a study published 27 March in the Proceedings of the National Academy of Sciences.

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Rinse and repeat

by  /  22 May 2012

Researchers typically use only one ‘cohort,’ a group of about three dozen mice, for a given set of experiments. When others repeat the experiments with a different set of animals, sometimes the results hold up, and sometimes they don’t.

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Genetics: SHANK1 mutations found in men with autism

by  /  11 May 2012

Researchers have identified deletions in SHANK1 — the third member of a gene family that is closely linked to autism — in five men with the disorder, they reported 4 May in the American Journal of Human Genetics. This is the first study linking SHANK1 mutations to people with autism.

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April 2012

Studies highlight promise of fragile X treatment

by  /  30 April 2012

A promising approach to treating fragile X syndrome could benefit people even after the critical window of early brain development, and alleviate core symptoms of autism, according to two studies published this month.

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Genetics: Environment modulates autism symptoms in mice

by  /  24 April 2012

Mutant mice with autism-like behaviors have fewer behavioral impairments when provided with toys, exercise wheels and contact with other mice, than do those that live in typical laboratory cages, according to a study published 5 April in Human Molecular Genetics. 

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Molecular mechanisms: Serotonin regulation linked to autism

by  /  18 April 2012

An autism-associated variant in a gene that regulates the chemical messenger serotonin leads to abnormal serotonin regulation and autism-like behaviors in mice. The results were published 3 April in the Proceedings of the National Academy of Sciences.

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November 2011

Mouse monopoly

by  /  25 November 2011

There are a host of problems with laboratory rodents that scientists rarely talk about, argues a fascinating series of articles in Slate magazine.

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Video: Birds do it for autism research

by  /  17 November 2011

Studying bird species such as the zebra finch can help researchers understand language difficulties in autism, Stephanie White told SFARI.org in a video interview at the 2011 Society for Neuroscience annual meeting in Washington, D.C.

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Researchers unveil seven new rat models of autism

by  /  16 November 2011

A large scientific research company debuted seven new rat models of autism Tuesday evening in Washington, D.C. Two of the models, one lacking FMR1 and the other lacking NLGN3, show some unexpected new characteristics.

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