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Spectrum: Autism Research News

Tag: whole-exome sequencing

July 2011

Genetics: FOXP2 important for early brain development

by  /  8 July 2011

FOXP2, a gene tied to autism and language disorders, is needed for proper wiring of the developing brain, according to a study published 7 July in PLoS Genetics.

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May 2011

Family sequencing study boosts two-hit model of autism

by  /  15 May 2011

A new analysis of children with autism and their unaffected parents provides the best evidence to date that mutations in multiple genes may work together to cause autism and related disorders.

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January 2011

Genetics: Spontaneous mutations lead to mental retardation

by  /  3 January 2011

Spontaneous mutations that change a single DNA base account for a large proportion of cases of unexplained mental retardation, according to a study published in the December Nature Genetics.

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November 2010

Decoding the exome points to new autism genes

by  /  16 November 2010

Sequencing the exomes — regions of the genome that code for proteins — of 18 individuals with autism has revealed new candidate genes for the disorder, researchers reported Sunday at the Society for Neuroscience annual meeting in San Diego.

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April 2010

Future of autism genetics is all in the family

by  /  30 April 2010

Two independent teams have identified the genetic culprits of three rare, inherited diseases by sequencing the genomes of several members of the same family. As the cost of whole-genome sequencing plummets, this family-based approach will reveal candidate genes not just for rare diseases but for common, complex disorders such as autism, experts say.

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All together now?

by  /  19 April 2010

On 7 April, a group of investigators conducting autism genome sequencing projects met at the New York Academy of Medicine, aiming to establish the ground rules for a potential Autism Sequencing Consortium.

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March 2010

Happy birthday, genome

by  /  31 March 2010

This summer will mark ten years since scientists sequenced the human genome. What have we gained from knowing those 3 billion base pairs?

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October 2008

In search of meaningful copy number variations

by  /  24 October 2008

In the past few months, researchers have published dozens of reports linking single-nucleotide polymorphisms (SNPs) with susceptibility to a range of common diseases.

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