Two new analyses help to explain why mutations to the chromosomal region 16p11.2 can lead to autism, intellectual disability or language difficulties.
Spectrum: Autism Research News
Tag: whole-exome sequencing
A trove of DNA sequences from 141,456 people — and counting — offers an unparalleled look at genetic variation.
Individuals with mutations in an autism gene called TRIO may have a range of conditions, including intellectual disability and anomalous head size.
People with attention deficit hyperactivity disorder may carry certain rare, harmful mutations in many of the same genes as people with autism.
The largest analysis of sequences from autistic people and their families implicates 184 genes in the condition — nearly doubling the previous estimate.
A new analysis challenges the idea that mutations in the sperm of older fathers lead to higher rates of autism among their children.
Spontaneous mutations that occur between genes may be as important in autism as those within genes.
A website called GeneMatcher has helped researchers identify a new gene for intellectual disability, developmental delay and autism.