A rare condition marked by a sudden and profound loss of skills is biologically distinct from other forms of autism.
Spectrum: Autism Research News
Tag: whole-exome sequencing
Variants of some mitochondrial genes may contribute to autism — in some cases, by teaming up with genes in the nucleus.
Whether a gene should be considered a ‘novel candidate’ for autism depends not just on whether it’s been linked to the condition before, but on the strength of that link.
A February study that tied several new genes to autism contained a large statistical error, according to a report from 14 independent researchers; the original team is working on issuing a correction.
Mutations in a gene called TRIP12 — which is involved in tagging proteins for destruction — can lead to intellectual disability, language delay and autism.
An analysis of whole genomes from more than 5,000 people has unearthed 18 new candidate genes for autism.
Understanding how mutations in genes linked to autism perturb the different versions of proteins the genes form could reveal new targets for treatments.