Skip to main content

Spectrum: Autism Research News

Tag: whole-exome sequencing

November 2015

Long-awaited databases reveal breadth of genetic variation

by  /  4 November 2015

Two massive efforts to sequence the DNA of more than 11,000 people together provide the most detailed picture yet of genetic variation in the general population.

0 Comments
October 2015

Analysis makes sense of missense mutations’ role in autism

by  /  12 October 2015

Analyzing thousands of sequences, researchers have homed in on miniscule portions of the genome that may be crucial in determining autism risk.

0 Comments

Dispatches from ASHG 2015

by  /  9 October 2015

These short reports from our reporter, Jessica Wright, give you the inside scoop on developments at the 2015 American Society of Human Genetics Annual Meeting.

0 Comments

Twin study unearths clues to role of environment in autism

by  /  8 October 2015

Researchers in Sweden are assembling a large group of identical twin pairs, with only one twin in each pair having autism.

0 Comments

Sequencing studies sharpen focus on key autism genes

by  /  1 October 2015

Two studies prioritize autism risk genes for further research and illuminate how different types of mutations may work together.

2 Comments
September 2015

Genetic tests, physical exam forecast autism diagnosis

by  /  17 September 2015

Combining two genetic tests with a physical exam may flag young children at risk for autism years earlier than behavioral assessments do.

2 Comments
August 2015

Software forecasts effects of mysterious mutations

by  /  26 August 2015

A new computer program predicts the effects of mutations in regions of the genome that control gene expression. Researchers can use the tool, called DeepBind, to gauge whether autism-linked mutations might block the genetic landing strips for regulatory proteins.

0 Comments

Control centers for genes rife with autism-linked DNA blips

by  /  3 August 2015

DNA sequences called enhancers — which boost the expression of genes from within or outside them — are enriched for genetic variants linked to autism, suggests a new study. The finding may help researchers understand how variants outside genes contribute to autism.

0 Comments
June 2015

Boys with autism inherit mutations from unaffected mothers

by  /  1 June 2015

Rare inherited mutations may contribute to autism in roughly 10 percent of boys with the disorder, according to a study published 11 May in Nature Genetics. These genetic glitches are primarily passed down from unaffected mothers.

6 Comments
May 2015

Rare regressive disorder is not autism, new findings suggest

by  /  15 May 2015

Children who are diagnosed with autism after drastically and suddenly losing cognitive abilities may actually have a distinct disorder, according to data presented yesterday at the 2015 International Meeting for Autism Research in Salt Lake City, Utah.

18 Comments