Over the course of a career spanning more than three decades, Huda Zoghbi has won almost every major biology and neuroscience research award that exists. More than 20 years since she discovered the gene behind Rett syndrome, she remains laser focused on unlocking the condition’s secrets and finding effective treatments.
Spectrum: Autism Research News
Tag: X chromosome
Methods that selectively increase levels of the Rett protein make for safer and more effective treatment strategies, some researchers say.
A new study pinpoints the genes and cell types that may underlie the atypical brain structure seen in people with genetic conditions linked to autism.
A gene therapy for Angelman syndrome stands at the forefront of efforts to treat autism-linked conditions that stem from single genes.
A new technique may reveal how mutations on the X chromosome alter various types of cells in the brain.
A new line of female mice may enable researchers to test gene-based therapies for Rett syndrome.
A modified version of the genetic engineering tool CRISPR may restore expression of the gene mutated in fragile X syndrome.
Differences in brain structure may distinguish boys with relatively mild features of fragile X syndrome from those with a severe form of the condition.
Drugs that block certain brain enzymes could help treat two conditions associated with autism.
A cannabis gel may ease features of fragile X syndrome, omega fatty acids show promise for autism in two trials, and oxytocin reinforces social behaviors through the brain’s reward pathway.