The brains of people with autism show high levels of inflammation compared with controls, suggests a study of postmortem brain tissue from 11 individuals with autism, presented at a poster session Monday at the Society for Neuroscience meeting in Chicago.
From parental age to infection during pregnancy, environmental elements can influence autism risk.
Mice carrying an autism-associated mutation show impaired social interactions and dramatic changes in brain size when their immune systems are activated, according to research presented yesterday at a poster session at the Society for Neuroscience meeting in Chicago.
Tracy Bale, associate professor of neuroscience at the University of Pennsylvania, talks about what she calls her “big soapbox issue”: the fallacious idea of a true animal model for a human psychiatric disease — and the pitfalls of over-interpreting rodent behavior.
Interested more in ideas than in dominating a crowded field, Michael Wigler decided to apply his expertise in cancer genetics to studying poorly understood features of autism.
A team of British researchers has garnered some of the first genetic evidence supporting their theory that sex hormones play a role in the development of autism.
Children with autism are no more likely than healthy children to have some of the gastrointestinal symptoms — such as diarrhea, acid reflux and abdominal discomfort — previously tied to the disorder, according to one of the first long-term investigations of the supposed link.
Several new genetic variants associated with schizophrenia lie in regions important for immune function and associated with autism. This suggests that both disorders stem partly from abnormal activation of the immune system, say some researchers.
Women who take prenatal vitamins and eat cereal supplemented with folic acid in the early months of pregnancy are less likely to have children with autism compared with women who consume less folate, suggests preliminary data from a survey presented today at the Society for Neuroscience conference.